Composite
Part:BBa_I756031:Design
Designed by: Omar Khan Group: iGEM07_Bay_Area_RSI (2007-10-25)
mLexA-dnaEn-p85alpha
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal EcoRI site found at 607
Illegal XbaI site found at 3258
Illegal PstI site found at 651
Illegal PstI site found at 1555 - 12INCOMPATIBLE WITH RFC[12]Illegal EcoRI site found at 607
Illegal PstI site found at 651
Illegal PstI site found at 1555
Illegal NotI site found at 633 - 21INCOMPATIBLE WITH RFC[21]Illegal EcoRI site found at 607
Illegal BglII site found at 537
Illegal BamHI site found at 617
Illegal XhoI site found at 640 - 23INCOMPATIBLE WITH RFC[23]Illegal EcoRI site found at 607
Illegal XbaI site found at 3258
Illegal PstI site found at 651
Illegal PstI site found at 1555 - 25INCOMPATIBLE WITH RFC[25]Illegal EcoRI site found at 607
Illegal XbaI site found at 3258
Illegal PstI site found at 651
Illegal PstI site found at 1555
Illegal NgoMIV site found at 1076 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 2812
Design Notes
A flexible GS Linker (GGGGS)x5 (or more) is required between the dnaEc and Syk. This was quite difficult to clone in with the FseI site used in the part.
Source
p85 from OpenBiosystems (Clone ID: 3979333) mLexA from pEG202 dnaEn from dnaE gene of Synechocystis sp.(split inteins)